if you are a "politically exposed person" on a level that the US gov is aware of your existense and keeping a check on you, then you're fucked, or atleast, part of your assets are.
For the rest of us, you need to do a risk assesment as
@Sols said, and analyze your situation carefully and go from there, but diversify, diversify, diversify, and don't manage all your assets under your own name.
For myself, my most successful investment by far, is the investement that I've done and led me to network with powerful figures specially in MENA and SEA. This kind of networking opens whole different paths for you, paths that you never now existed or would work in real life scenarios, and I'm grateful for these relationships that helped me be who I'm today.
But regarding sanctions and whatnot, having a second passport and residency in "non-allied/neutural" countries helps a lot, Countries that don't take sides and only care about their own benefits, these countries can be a "Foundation" for future investments in most parts of the world.
Of course, this will requires some research and actual work on the ground, but later, you will find that everything will be a smooth sail from there.
So to summarize, second passport, residency in a neutural country (not switzerland, they are far from being "neutral" ) and diversified assets under different names/structures.
For crypto, what can I say! the past couple of weeks showed me that, if these Clown f*****s really want to f**k the crypto market and turn it upside down, they can, they really can, they have all the power to do so, and they can ban and criminalize dealing with crypto and any entity that deals with crypto.
So, forget about exchanges with swift, IBANs, visa/mc...etc. we will have nothing, and you will find the whole market crashing like a row of dominos in a matter of minutes.
Here is the thing, people are f lazy and they want convenience more than anything else, I'm talking about "venmo" or "cash up" experience, pull these things away from them and you will have ghosted platforms.
but but what about"P2P" Exchanges? they can't ban these right? Nope, they absolutely can ban them, they just need to freeze their owner's assets, and these platforms will be closed the next day.
It's fucking annoying how the US controls the rest of the world with a piece of paper and an ink pen, they didn't even need to move an inch and they fucked the economy of a nuclear powerhouse.
But Crypto? yeah yeah, crypto my a*s, Most people in this forum know that I'm one of the biggest crypto fans out there, but I don't like living in a fantasy world, and we saw how in a couple of days the US and co sent russia back to the stone age, and we are talking about russia whom is a major player in the global stage, but crypto? lol, crypto needs liquidity, and where are we gonna get this massive liquidity from? from fiat, right? so how are we gonna get this liquidity from fiat if it's prohibited by international law to do so? I think we have a chance to get this liquidity from the aladin's genie than from any reputable institutional investor.
and let's be honest, if global governments ban crypto, the only people who are gonna use crypto are drug dealers, drug users, tax evaders, war lords, Blackmarket operators and human trafficers. and no investor - be it small, big or whatever - will touch crypto or any technology that has "crypto" in it's name. And I don't know if you want your name to be assosiated with these kind of people :/
Having said that, I still hold and invest in various crypto projects but I'm not delusinal, and people who think crypto is the be all or the end all, need a quick reailty check becaue otherwise, I don't know what to fucking tell them if they've not learnt a damn thing from the recent events that happened and still going on to this day.
But crypto this crypto that, give me a fucking break.